Initiation of follicular atresia: gene networks during early atresia in pig ovaries
نویسندگان
چکیده
منابع مشابه
Expression and activity of Apaf1 and caspase-9 in granulosa cells during follicular atresia in pig ovaries.
Apoptosis in granulosa cells plays a crucial role in ovarian follicular atresia, but the intracellular regulating mechanism, especially the mitochondrion-dependent apoptosis signalling pathway, is still largely unknown. This study examined whether the mitochondrial pathway is associated with granulosa cell apoptosis during atresia in pig ovaries. Both mRNAs of caspase-9 and apoptotic protease-a...
متن کاملOvarian Follicular Atresia
Throughout ovarian development and function in mammals, a highly orchestrated, periodic process known as follicular atresia occurs that destroys and eliminates follicles and oocytes from the ovary. Follicular atresia is pervasive. In humans, it is estimated to account for 99.9% of the loss of oocytes from development of the fetal ovary until reproductive senescence (Baker, 1963; Faddy et al., 1...
متن کاملThecal vasculature and oocyte maturation during follicular atresia in the sheep and pig.
During follicular atresia in the sheep and pig there is a marked reduction in the vasculature of the theca interna underlying the membrana granulosa. In the sheep there is no reduction of thecal blood vessels adjacent to the cumulus which remains viable. By contrast, in the pig the cumulus degenerates during atresia and the underlying thecal vasculature is greatly diminished. However, despite l...
متن کاملHistological observation of the development of follicles and follicular atresia in immature rat ovaries.
To clarify the development of follicular growth and atresia in the immature ovary, rats. ovaries and blood were removed at fixed points during the period from 0 to 35 days after birth (Day 0 to Day 35). The ovaries were immunohistochemically examined, and blood concentrations of serum follicle-stimulating hormone (FSH) and estrogen (E) were measured. We investigated how time-course changes in f...
متن کاملFollicular populations, recruitment and atresia in the ovaries of different strains of mice.
Follicular atresia is a key event in the selection of the ovulatory follicles and occurs during all developmental stages. The aims of the study were to evaluate the follicular population as well as the rates of follicular recruitment and atresia in different strains of mice. Ovaries were obtained from four strains of mice: G1/ Swiss, G2/ F1 Swiss×C57BL/6, G3/ inbred strain C57BL/6, and G4/ F1 C...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2018
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-18-0058